PURIHILO PN — Hybrid Moisturizing & Revitalizing Complex

PURIHILO PN is an advanced skin rejuvenation injectable that combines high-molecular and low-molecular hyaluronic acid (HA) with sodium polynucleotide (PN) using patented ABEP hybrid stabilization technology.

Unlike conventional fillers, it contains no BDDE or other chemical cross-linkers, ensuring a completely biocompatible, safe, and natural formulation.

Composition (per 2.5 mL vial)

• High-molecular HA — 40 mg

• Low-molecular HA — 40 mg

• Sodium Polynucleotide — 25 mg

• Phosphate-buffered saline q.s.

Mechanism of Action

Through hybrid stabilization of H-HA and L-HA, PURIHILO PN restores the acid-base balance of the extracellular matrix and activates the skin’s natural regeneration pathways.

Polynucleotides stimulate fibroblast activity, collagen and elastin synthesis, and the release of growth factors such as EGF, FGF, IGF, and VEGF-A, improving elasticity, hydration, and dermal density.

Benefits

• Deep and long-lasting hydration and revitalization

• Lifting and tightening effect by remodeling the skin’s structure

• Wrinkle reduction and improved skin tone

• Tissue regeneration in areas with acne scars or atrophic changes

• Minimal inflammatory response due to low viscosity and high purity

• Restores elasticity and luminosity for a naturally youthful appearance

Indications

• Loss of skin elasticity and firmness

• Fine lines and wrinkles

• Dull, dehydrated, or sagging skin

• Post-acne scars and dermal atrophy

• Suitable for face, neck, décolletage, and hands

Treatment Protocol

• 2 sessions at 1-month intervals

• BAP (Bio-Aesthetic Points) technique recommended for face, neck, or hands

• Injection depth: superficial subcutaneous layer

• Provides visible improvements after the first session, with optimal results after the second

Clinical Results

Scientific studies confirm a significant increase in skin hydration and elasticity, as well as visible reduction in wrinkle depth within 4–8 weeks.

Histological analysis shows enhanced collagen type I synthesis and accelerated tissue repair in dermal fibroblasts.

Summary

PURIHILO PN represents a new generation of hybrid biorevitalizing injectables that combine powerful hydration, tissue regeneration, and collagen stimulation—without the risks of cross-linked fillers.

The result is smoother, firmer, and deeply revitalized skin with a healthy, luminous glow.